Journal of Biology and Today's World

Use of Haplotype assembly problem in eliminating SNPs from ApoE4 gene of the human genome

Abstract

Author(s): Monica Shekhar, Harleen Jabbal, Jasleen Kaur, R.Selva kumar

"The human genomic sequence comprises of chromosomal DNA molecules. A DNA sequence is a double helical structure consisting of molecules of sugar, phosphate and nucleotides A, T, G, and C. A Single Nucleotide Polymorphism (SNP) is defined as a difference of a nucleotide between the genomic sequences of any biological species. The haplotype assembly problem was used as a solution methodology to eliminate SNPs in the ApoE gene of the human genomic sequence."

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