Journal of Biology and Today's World

Nanotechnological Approaches for Enhancing the Oral Bioavailability of Curcumin

Abstract

Author(s): Razieh Nazari-Vanani, Naghmeh Sattarahmady, Hossein Heli

Turmeric is a member of the ginger family (Zingiberaceae). It contains i) curcumin, ii) demethoxycurcumin, and iii) bisdemethoxycurcumin. Curcumin is the active component in the turmeric and has promising pharmacological properties. Despite promising clinical potentials, it has limited clinical use due to poor bioavailability. Thus, improving the water-solubility and bioavailability of curcumin are very interested. One of the approaches to overcome low bioavailability of curcumin is the formulation of curcumin into nanoscale drug delivery systems working as nanocarriers. They are emerging strategies for therapeutic agents that cannot be used effectively as conventional drug formulations. In addition, they have many advantages such as improving the stability, ease of preparation, reducing the dose, reduction of side effects, and solubility enhancement. For this purposes, the aspects and role of nanoscale drug delivery systems in the solubility enhancement of curcumin was presented and discussed in this review.

Share this article

Reach Us

Lexispublisher
Avenue Roger Vandendriessche 18,
1150 Brussels, Belgium
Toll Free +32 (800) 709-48

Contact Us

E-Mail: [email protected]

© Lexispublisher 2019 | Creative Commons License Open Access Journals by Lexispublisher is licensed under a Creative Commons Attritbution 4.0 International License

Top