Journal of Biology and Today's World

Evaluation of Antibacterial Activity of Ethanolic Extract of Malva neglecta and Althaea officinalis L. on Antibiotic-Resistant Strains of Staphylococcus aureus

Abstract

Author(s): Abolfazl Jafari-Sales, Behboud Jafari, Javad Sayyahi, Tahereh Zohoori-Bonab

"With increasing awareness of the dangerous effects of synthetic antibiotics, the demand for natural herbal drugs and cheap without side effects has increased. The present study aims to investigate the antibacterial effect of ethanolic extract of Malva neglecta and Althaea officinalis L. on antibiotic-resistant strains of Staphylococcus aure-us. After collecting herbs and approval of its scientific name by botanists of Iranian Agriculture Organization, the extract of Malva neglecta and Althaea officinalis L were prepared by vacuum distillation procedure. Then minimum inhibitory concentration and minimum bactericidal concentration (MBC) of the extracts were determined on S. aureus strains isolated from patients with broth micro dilution and agar dilution method. Results showed that MIC/MBC of ethanolic extracts of Malva neglecta and and Althaea officinalis L. against S. aureus were 6.5/13 mgml-1 and 3.2/6.5 mgml-1, respectively. These findings suggest that Malva neglecta and Althaea officinalis L. can be con-sidered as a group of herbs with anti-bacterial properties. Thus, it can be used widely in traditional medicine in this regard."

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